Deninu Kue (pronounced "Deneh-noo-kweh"), means "moose island". It is a "settlement corporation" in the South Slave Region of the Northwest Territories, Canada. The community is situated at the mouth of the Slave River, on the shore of Great Slave Lake, and at the end of Fort Resolution Highway (Highway 6).
It is the oldest documented community in the Northwest Territory, and was a key link in the fur trade's water route north. Formerly known as Fort Resolution, it is designated as a national historic site, due to its importance to aboriginal culture and fur trade history. Population is 484 according to the 2006 Census. The majority of people are of Dene or Métis descent. The predominant languages are English, Chipewyan and Michif.
Local people engage in fishing, moose hunting, and trapping of ptarmigan and rabbit year-round.
Fort Resolution is represented by the Deninu Kue First Nation and are part of the Akaitcho Treaty 8 Tribal Corporation.
There are four First Nations within the Akaitcho Territory. They are: